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Treatment Resistant Depression

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Treatment Resistant Depression services offered in Sandy Springs and Alpharetta, GA


There’s no single reason why you would get depression, nor is there one solution that works for everyone. If nothing else is helping, contact Breakthru Psychiatric Solutions in Sandy Springs and Alpharetta, Georgia. Our doctors specialize in treatment-resistant depression, using innovative therapies like transcranial magnetic stimulation (TMS), IV ketamine, Spravato, and Vagus Nerve Stimulation (VNS). We work with you to create a plan that will succeed in breaking through your treatment-resistant depression. To find out more, call Breakthru Psychiatric Solutions or request an appointment online today.

Treatment Resistant Depression Q & A

What is treatment-resistant depression? Treatment-resistant depression (TRD) occurs when your condition does not improve despite trying various combinations of therapies. This issue affects more than 40% of patients with depression. While many people benefit from talk therapies and medications, some struggle to find effective treatments. Interpersonal psychotherapy and cognitive behavioral therapy (CBT) can help address life issues and teach coping techniques. Antidepressant medications are often crucial for recovery, but not everyone finds one that works. If you've tried several therapies and medications without success, our doctors' expertise in TRD may help.
Why would I have treatment-resistant depression? There is no single cause for depression, and no one treatment works for everyone. Factors contributing to TRD include traumatic life events, chronic health problems, and genetic predisposition. Depression is often linked to a chemical imbalance in the brain, with lower levels of neurotransmitters like serotonin and dopamine. This imbalance can either cause or result from depression, making it challenging to treat.
How is treatment-resistant depression treated?
  • Transcranial Magnetic Stimulation (TMS): TMS uses magnetic fields to stimulate brain areas linked to mood regulation. Dr. Giles places an electromagnetic coil on your head to deliver painless pulses.
  • IV Ketamine Therapy: Ketamine, an anesthetic, has significant effects on depression. It is administered through an intravenous (IV) line, with the medication dripping into your bloodstream over 30 minutes.
  • Spravato®: Spravato is an FDA-approved nasal spray containing esketamine, a refined form of ketamine. It is used under medical supervision alongside antidepressant medication.
  • Vagas Nerve Stimulation (VNS): VNS involves implanting a small device in your chest that sends mild pulses to the vagus nerve, which helps regulate mood.

To find out how you can overcome treatment-resistant depression, call Breakthru Psychiatric Solutions today or request an appointment online.

*Breakthru does not provide medication management and offers the interventional therapies listed above in conjunction with the support of your primary psychiatrist or PCP.